VcMMAE

产品编号: DC7556 Featured
VcMMAE
结构式
646502-53-6
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中国地区超过5000个高品质化合物库存
应用领域
VcMMAE (mc-vc-PAB-MMAE) 是抗体药物复合体的一部分 (drug-linker conjugate for ADC),具有抗癌活性,它由 MMAE (一种 tubulin 抑制剂) 和 Vc 连接而成。
Cas No.: 646502-53-6
名称:
别名: VC-MMAE,Vc MMAE
SMILES: CC[C@H](C)[C@@H]([C@@H](CC(=O)N1CCC[C@H]1[C@@H]([C@@H](C)C(=O)N[C@H](C)[C@H](C2=CC=CC=C2)O)OC)OC)N(C)C(=O)[C@H](C(C)C)NC(=O)[C@H](C(C)C)N(C)C(=O)OCC3=CC=C(C=C3)NC(=O)[C@H](CCCNC(=O)N)NC(=O)[C@H](C(C)C)NC(=O)CCCCCN4C(=O)C=CC4=O
分子式: C68H105N11O15
分子量: 1316.63
纯度:
保存条件: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description:
In Vivo:
In Vitro:
References: VcMMAE is an antibody-drug conjugate (ADC) with potent antitumor activity by using the anti-mitotic agent, monomethyl auristatin E (MMAE), linked via the lysosomally cleavable dipeptide, valine-citrulline (vc). IC50 value: Target: Antibody-drug conjugate;
Kinase Assay:
Cell Assay:
Animal Administration:
References:
MSDS
TITLE DOWNLOAD
MSDS_1821_DC7556_646502-53-6
COA
LOT NO. DOWNLOAD
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