Importazole

产品编号: DC10027 Featured
Importazole
结构式
662163-81-7
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中国地区超过5000个高品质化合物库存
应用领域
Importazole是核转运受体importin-β的小分子抑制剂。
Cas No.: 662163-81-7
名称: N-(1-Phenylethyl)-2-(pyrrolidin-1-yl)quinazolin-4-amine
别名:
SMILES: CC(C1=CC=CC=C1)NC2=NC(=NC3=CC=CC=C32)N4CCCC4
分子式: C20H22N4
分子量: 318.42
纯度:
保存条件: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description:
In Vivo:
In Vitro:
References: Importazole is an inhibitor of importin-β transport receptors. During interphase, the transport receptor importin-β carries cargoes into the nucleus, where RanGTP releases them. Importazole somehow disrupts the importin/RAN interaction. Importazole is selective among other transporters. Compounds are imported into, but not out of, cells.
Kinase Assay:
Cell Assay:
Animal Administration:
References:
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
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