Apatinib (free base)

产品编号: DC8465 Featured
Apatinib (free base)
结构式
811803-05-1
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中国地区超过5000个高品质化合物库存
应用领域
Apatinib free base (YN968D1 free base) 是一种口服生物可利用的酪氨酸激酶抑制剂,选择性靶向VEGFR-2 (IC50=1 nM)。Apatinib free base (YN968D1 free base) 是治疗晚期或转移性胃癌的抗血管生成药物。Apatinib free base (YN968D1 free base) 能有效抑制 Ret、c-Kit 和 c-Src 活性,IC50 值分别为 13,429,530 nM。Apatinib free base (YN
Cas No.: 811803-05-1
名称: N-(4-(1-cyanocyclopentyl)phenyl)-2-((4-methylpyridin-3-yl)amino)nicotinamide
别名: Apatinib; YN968D1
SMILES: C(NC1=CC=C(C(C#N)2CCCC2)C=C1)(=O)C1=C(NC2=C(C)C=CN=C2)N=CC=C1
分子式: C24H23N5O
分子量: 397.47232
纯度:
保存条件: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description:
In Vivo:
In Vitro:
References: Apatinib is an orally bioavailable, small-molecule receptor tyrosine kinase inhibitor with potential antiangiogenic and antineoplastic activities.
Kinase Assay:
Cell Assay:
Animal Administration:
References:
MSDS
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