Elagolix

产品编号: DC10032 Featured
Elagolix
结构式
832720-36-2
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中国地区超过5000个高品质化合物库存
应用领域
Elagolix sodium 是一种人的 GnRH 受体 (GnRHR) 拮抗剂,其 IC50 和 Ki 值分别为 0.25 和 3.7 nM。
Cas No.: 832720-36-2
名称: 4-[[(1R)-2-[5-(2-fluoro-3-methoxyphenyl)-3-[[2-fluoro-6-(trifluoromethyl)phenyl]methyl]-4-methyl-2,6-dioxopyrimidin-1-yl]-1-phenylethyl]amino]butanoic acid
别名: NBI 56418, NBI56418,NBI-56418
SMILES: CC1=C(C(=O)N(C(=O)N1CC2=C(C=CC=C2F)C(F)(F)F)C[C@@H](C3=CC=CC=C3)NCCCC(=O)[O-])C4=C(C(=CC=C4)OC)F.[Na+]
分子式: C32H29F5N3O5Na
分子量: 653.57
纯度:
保存条件: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description:
In Vivo:
In Vitro:
References: Elagolix is a Gonadotropin-Releasing Hormone (GnRH) Antagonist. Elagolix inhibits gonadatropin releasing hormone (GnRH) receptors in the pituitary gland and ultimately reduces circulating sex hormone levels. To date, elagolix has been studied in over 20 clinical trials totaling more than 1,000 subjects. A Phase 2a trial of elagolix For the treatment of uterine fibroids is also ongoing. Endometriosis can be a debilitating disease that affects millions of women around the world and the exploration of new treatments could offer other options For women with this diseaseFor the detailed information of Elagolix, the solubility of Elagolix in water, the solubility of Elagolix in DMSO, the solubility of Elagolix in PBS buffer, the animal experiment (test) of Elagolix, the cell expriment (test) of Elagolix, the in vivo, in vitro and clinical trial test of Elagolix, the EC50, IC50,and Affinity of Elagolix, Please contact DC Chemicals.
Kinase Assay:
Cell Assay:
Animal Administration:
References:
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
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