AC 55541

产品编号: DC7698 Featured
AC 55541
结构式
916170-19-9
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中国地区超过5000个高品质化合物库存
应用领域
AC-55541是高选择性的蛋白酶激活受体 2 (PAR2) 激动剂 (pEC50=6.7),在其他 PAR 亚型或 30 种参与伤害感受和炎症的受体中没有活性。AC-55541 在 PI 水解测定和 Ca2+ 动态测定中的 pEC50 值为 5.9 和 6.6,并且在体内表现出伤害感受器活性。
Cas No.: 916170-19-9
名称: (2E)-2-[1-(3-Bromophenyl)ethylidene] α-(benzoylamino)-3,4-dihydro-4-oxo-1-phthalazineacetic acid hydrazide
别名: AC55541, AC-55541
SMILES: C/C(=N\NC(=O)C(C1=NNC(=O)C2=CC=CC=C21)NC(=O)C3=CC=CC=C3)/C4=CC(=CC=C4)Br
分子式: C25H20BrN5O3
分子量: 518.36
纯度:
保存条件: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description:
In Vivo:
In Vitro:
References: Potent and selective protease-activated receptor 2 (PAR2) agonist (pEC50 = 6.7) that displays no activity at other PAR subtypes or at over 30 other receptors involved in nociception and inflammation. Stimulates cell proliferation, PI hydrolysis and Ca2+ m
Kinase Assay:
Cell Assay:
Animal Administration:
References:
MSDS
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