| DC31023 |
PT2977
|
PT2977 (MK-6482) is an orally active and selective HIF-2α inhibitor with an IC50 of 9 nM. PT2977, as a second-generation HIF-2α inhibitor, |
| DC20000 |
LR-90
|
LR-90 is an advanced glycation end product (AGE) inhibitor, inhibits inflammatory responses in human monocytes. LR-90 is also used in the research of diabetic animal model. |
| DC11219 |
Hoechst 33342
|
Hoechst染料是DNA蓝色荧光染料，Hoechst 33342是其中一种。 |
| DC27035 |
EIDD-2801
|
EIDD-2801 is an isopropylester prodrug of the ribonucleoside analog N4-hydroxycytidine (NHC, EIDD-1931) that has shown broad anti-influenza virus activity in cultured cells and mice. |
| DC26231 |
Furin Inhibitor II
|
Hexa-D-arginine (Furin Inhibitor II) 是一种稳定的 furin 抑制剂，对 furin，PACE4 和 PC1 的 Ki 值分别为 106 nM，580 nM 和 13.2 μM。Hexa-D-arginine 在体外和体内均可阻断假单胞菌外毒素 A 和炭疽毒素的毒性。 |
| DC27050 |
GSK2983559
|
GSK2983559 free acid (compound 3) 是一种高效、特异性的，口服有效的受体相互作用蛋白 2 (RIP2) 激酶抑制剂。GSK2983559 free acid 在体内和人类炎症性肠病外植体样本中，具有良好的阻断多种促炎细胞因子反应活性。 |
| DC21672 |
SNAP-94847 hydrochloride
|
SNAP 94847 是一种新型的，高亲和力的选择性黑色素浓缩激素受体 1 (MCHR1) 拮抗剂，其 (Ki= 2.2 nM, Kd=530 pM)，它对 MCHα1A 和 MCHD2 受体分别显示出 >80 倍和 >500 倍的选择性。 SNAP 94847 以高亲和力与小鼠和大鼠 MCHR1 结合，与其他 GPCR，离子通道，酶和转运蛋白的交叉反应性很小。 |
| DCAPI1051 |
Arbidol HCl (Umifenovir)
|
Arbidol hydrochloride (Umifenovir hydrochloride) is an potent inhibitor of COVID-19. |
| DC8759 |
Thiamet G
|
Thiamet G is a potent and selective inhibitor of O-GlcNAcase that demonstrates a Ki value of 21 nM. |
| DCAPI1390 |
Atovaquone (Atavaquone)
|
Atovaquone is a medication used to treat or prevent for pneumocystis pneumonia, toxoplasmosis, malaria, and babesia. |
