Borussertib is a potent, first-in-class, covalent-allosteric AKT inhibitor.

A homoisoflavanone found in Caesalpinia sappan, a potent, selective IMPDH2 inhibitor that covalently binds to Cys140 with Kd of 3.944 nM, almost 10 times lower than the Kd of binding to IMPDH1.

BKI-1369 is an effective bumped kinase inhibitor (BKI), inhibits Theileria equi in vitro and reduces parasite burden and disease severity in the gnotobiotic pig model.

CCG-50014 (CCG50014) is a potent, selective, covalent inhibitor of RGS4 with IC50 of 30 nM.

A novel potent, selective KCNQ2/Q3 (Kv7.2/Kv7.3) potassium channel opener/activator with EC50 of 0.38 uM..

FB23-2 is a potent, selective inhibitor of the mRNA N 6-methyladenosine (m 6A) demethylase FTO, directly bind to FTO, inhibits FTO demethylation of m6 A in RNA in vitro with IC50 of 2.6 uM.

Oseltamivir acid (GS 4071, Ro 64-0802, Oseltamivir carboxylate) is a potent inhibitor of influenza neuraminidase (NA) with Ki of <1 nM for both A and B strains..

JNJ303 is a potent, specific delayed rectifier potassium current I(Ks) blocker with IC50 of 64 nM, shows no effects on other cardiac channels (IC50=3.3, >10, 11.1 and 12.6 uM for Na, ICa, Ito and IKr currents).

AK778 (Col001) is a small-molecule compound that inhibits the interaction of Hsp47 with collagen, competitively inhibits the interaction and causes the inhibition of collagen secretion by destabilizing the collagen triple helix. .

G10 (STING Agonist 1) is a novel human-specific STING agonist.

TVB-2640 is an orally bioavailable fatty acid synthase (FASN) inhibitor, with potential antineoplastic activity.

DDD107498, also known as DDD 498, is a multiple-stage antimalarial agent that inhibits protein synthesis.

JA2-3 (NSC29192) is a potent dose-dependent inhibitor of PARG with IC50 of 0.1 mM.

JA2120 (NSC81474) is a potent inhibitor of PARG with IC50 of 25.7 μM.

sCGT990 is a novel inhibitor of ENL-YEATS.

DS-1001b is a mutant IDH-1 (Isocitrate Dehydrogenase-1) inhibitor extracted from patent WO2016052697A1, Example 168, and has antitumor activity.

nAChR agonist 1 is a potent, brain-permeable, and orally efficacious positive allosteric modulator of α7 nicotinic acetylcholine receptor (α7 nAChR).

FK962 is an enhancer of somatostatin release, exerts cognitive-enhancing actions. Anti-dementia properties.

Decoglurant (RO4995819) is a negative allosteric modulator of mGluR2 and mGluR3. Decoglurant is developed as an antidepressant.

CIN-16645 is a cationic lipids useful in the delivery of biologically active agents to cells and tissues.

GRP-60367 is a first-in-class direct-acting RABV inhibitor.

WP1122 is a candidate drug to treat SARS-COV-2(COVID-19) .