| Cas No.: | 1009820-21-6 |
| 名称: | 5-(3-chlorophenylamino)benzo[c][2,6]naphthyridine-8-carboxylicacid |
| 别名: | Silmitasertib; CX 4945; CX4945 |
| SMILES: | C1=CC(=CC(=C1)Cl)NC2=C3C=CN=CC3=C4C=CC(=CC4=N2)C(=O)O |
| 分子式: | C19H12ClN3O2 |
| 分子量: | 349.77 |
| 纯度: | |
| 保存条件: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: | |
| In Vivo: | |
| In Vitro: | |
| References: | CX-4945 is selective For CK2, as it only inhibits 7 of the 238 kinases by more than 90% at concentration of 0.5 μM, which is 500-fold greater than the IC50 of CK2. Although in cell-free systems CX-4945 inhibits FLT3, PIM1, and CDK1 with IC50 of 35 nM, 46 |
| Kinase Assay: | |
| Cell Assay: | |
| Animal Administration: | |
| References: |




