MK-5108
产品编号: DC7466
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应用领域
MK-5108是高效和特异性的极光激酶A抑制剂，IC50 值为0.064 nM。
| Cas No.: |
1010085-13-8 |
| 名称: |
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| 别名: |
MK 5108; VX-689; VX 689; MK5108; VX689 |
| SMILES: |
FC(C(Cl)=CC=C1)=C1O[C@H](CC2)CC[C@@]2(C(O)=O)CC3=CC=CC(NC4=NC=CS4)=N3 |
| 分子式: |
C22H21ClFN3O3S |
| 分子量: |
461.94 |
| 纯度: |
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| 保存条件: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: |
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| In Vivo: |
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| In Vitro: |
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| References: |
MK-5108 inhibits Aurora-A activity in an ATP-competitive manner. MK-5108 shows robust selectivity against the other family kinases Aurora-B (220-fold) and Aurora-C (190-fold) in the biochemical assay. MK-5108 also reveals high selectivity For Aurora-A ov |
| Kinase Assay: |
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| Cell Assay: |
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| Animal Administration: |
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| References: |
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MSDS
COA
| LOT NO. |
DOWNLOAD |
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| 2018-0101 |
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询盘
