ARN2966(2-PMAP)
产品编号: DC9345
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应用领域
ARN2966是一个高效的，针对APP表达的转录后调节剂，降低APP的表达从而是Aβ的量降低。
| Cas No.: |
102212-26-0 |
| 名称: |
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| 别名: |
ARN-2966;ARN 2966 |
| SMILES: |
OC1=CC=CC=C1NCC2=NC=CC=C2 |
| 分子式: |
C12H12N2O |
| 分子量: |
200.2365 |
| 纯度: |
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| 保存条件: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: |
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| In Vitro: |
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| References: |
ARN2966 is a potent post-transcriptional modulator of APP expression; reduces expression of APP with resultant lower production of Aβ.
This potent post-transcriptional modulation of APP expression differs from other mechanisms such as inhibition of secretases. Secretase inhibitors have been pursued as disease modifying strategies by a number of pharmaceutical firms but they have encountered numerous setbacks during clinical development. ARN2966 is non toxic, orally absorbable, blood-brain-barrier penetrable, and effective in vitro and in vivo. |
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MSDS
| TITLE |
DOWNLOAD |
| MSDS_2639_DC9345_102212-26-0 |
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COA
| LOT NO. |
DOWNLOAD |
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询盘
