我们的合作伙伴:
中国地区超过5000个高品质化合物库存
应用领域
SGX-523 is a selective Met inhibitor with IC50 of 4 nM, no activity to BRAFV599E, c-Raf, Abl and p38α.
| Cas No.: |
1022150-57-7 |
| 名称: |
6-(6-(1-methyl-1H-pyrazol-4-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-ylthio)quinoline |
| 别名: |
SGX523; SGX 523 |
| SMILES: |
CN1N=CC(C2=NN3C(SC4=CC5=C(N=CC=C5)C=C4)=NN=C3C=C2)=C1 |
| 分子式: |
C18H13N7S |
| 分子量: |
359.41 |
| 纯度: |
|
| 保存条件: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: |
|
| In Vivo: |
|
| In Vitro: |
|
| References: |
SGX-523 belongs to the class of c-Met/hepatocyte growth factor receptor (HGFR) tyrosine kinase inhibitors. SGX-523 stabilizes MET in a unique inactive con Formation that is inaccessible to other protein kinases, suggesting an explanation For its selectiv |
| Kinase Assay: |
|
| Cell Assay: |
|
| Animal Administration: |
|
| References: |
|
MSDS
| TITLE |
DOWNLOAD |
| MSDS_3421_DC7294_1022150-57-7 |
|
COA
| LOT NO. |
DOWNLOAD |
|
|
询盘
