BMS777607
产品编号: DC7376
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应用领域
BMS 777607 是一种 Met-related 抑制剂，能够抑制 c-Met，Axl，Ron 和 Tyro3 的活性，IC50 值为 3.9 nM，1.1 nM，1.8 nM 和 4.3 nM。
| Cas No.: |
1025720-94-8 |
| 名称: |
N-[4-(2-amino-3-chloropyridin-4-yl)oxy-3-fluorophenyl]-4-ethoxy-1-(4-fluorophenyl)-2-oxopyridine-3-carboxamide |
| 别名: |
BMS777607; BMS-777607，BMS 777607 |
| SMILES: |
NC1C(Cl)=C(OC2C=CC(NC(C3=C(OCC)C=CN(C4C=CC(F)=CC=4)C3=O)=O)=CC=2F)C=CN=1 |
| 分子式: |
C25H19ClF2N4O4 |
| 分子量: |
512.89 |
| 纯度: |
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| 保存条件: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: |
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| In Vitro: |
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| References: |
BMS-777607, a Met tyrosine kinase inhibitor, is an inhibitor of MET tyrosine kinase with potential antineoplastic activity. MET tyrosine kinase inhibitor BMS-777607 binds to c-Met protein, or hepatocyte growth factor receptor (HGFR), preventing binding of |
| Kinase Assay: |
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| Cell Assay: |
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| Animal Administration: |
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| References: |
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MSDS
COA
| LOT NO. |
DOWNLOAD |
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| 2018-0101 |
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询盘
