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Lifitegrast(SAR 1118)

产品编号: DC8224 Featured
Lifitegrast(SAR 1118)
结构式
1025967-78-5
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中国地区超过5000个高品质化合物库存
应用领域
Lifitegrast (SAR 1118) 是整合素淋巴细胞功能相关抗原-1(LFA-1)的拮抗剂; 抑制Jurkat T细胞附着于ICAM-1的IC50为2.98nM。
化学性质生物活性化合物的使用COA & MSDS相关产品产品说明书
Cas No.: 1025967-78-5
名称:
别名: SAR-1118,SAR1118
SMILES: CS(C1C=C(C[C@@H](NC(C2C(Cl)=C3C(CN(C(C4C=CC5C=COC=5C=4)=O)CC3)=CC=2Cl)=O)C(O)=O)C=CC=1)(=O)=O
分子式: C29H24Cl2N2O7S
分子量: 615.49
纯度:
保存条件: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description:
In Vivo:
In Vitro:
References: SAR 1118 is a potent tetrahydroisoquinoline (THIQ)-derived LFA-1/ICAM-1 antagonist for treating dry eye. For the detailed information of Lifitegrast(SAR 1118), the solubility of Lifitegrast(SAR 1118) in water, the solubility of Lifitegrast(SAR 1118) in DMSO, the solubility of Lifitegrast(SAR 1118) in PBS buffer, the animal experiment (test) of Lifitegrast(SAR 1118), the cell expriment (test) of Lifitegrast(SAR 1118), the in vivo, in vitro and clinical trial test of Lifitegrast(SAR 1118), the EC50, IC50,and affinity,of Lifitegrast(SAR 1118), For the detailed information of Lifitegrast(SAR 1118), the solubility of Lifitegrast(SAR 1118) in water, the solubility of Lifitegrast(SAR 1118) in DMSO, the solubility of Lifitegrast(SAR 1118) in PBS buffer, the animal experiment (test) of Lifitegrast(SAR 1118), the cell expriment (test) of Lifitegrast(SAR 1118), the in vivo, in vitro and clinical trial test of Lifitegrast(SAR 1118), the EC50, IC50,and affinity,of Lifitegrast(SAR 1118), Please contact DC Chemicals.
Kinase Assay:
Cell Assay:
Animal Administration:
References:
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
产品编号 产品名称 应用领域
DC8224 Lifitegrast(SAR 1118) Lifitegrast (SAR 1118) 是整合素淋巴细胞功能相关抗原-1(LFA-1)的拮抗剂; 抑制Jurkat T细胞附着于ICAM-1的IC50为2.98nM。
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