GSK923295
产品编号: DC7812
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应用领域
GSK-923295 是一种特异性的变构着丝粒相关蛋白-E (CENP-E) 驱动蛋白 ATPase 活性抑制剂，作用于人类和犬类此酶，Ki 分别为 3.2±0.2 nM 和 1.6±0.1 nM。
| Cas No.: |
1088965-37-0 |
| 名称: |
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| 别名: |
GSK923295,GSK-923295,GSK923295 |
| SMILES: |
C(N[C@H](CC1=CC=C(C2=CN3C(=N2)C([C@H](O)C)=CC=C3)C=C1)CNC(CN(C)C)=O)(=O)C1=CC=C(OC(C)C)C(Cl)=C1 |
| 分子式: |
C32H38ClN5O4 |
| 分子量: |
592.13 |
| 纯度: |
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| 保存条件: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: |
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| In Vivo: |
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| In Vitro: |
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| References: |
GSK923295 is the first potent and selective inhibitor of the mitotic kinesin centromere-associated protein-E (CENP-E). GSK923295 is uncompetitive with both ATP and microtubules (MT), inhibiting CENP-E MT-stimulated ATPase activity with a Ki of 3.2 nM, hi |
| Kinase Assay: |
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| Cell Assay: |
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| Animal Administration: |
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| References: |
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MSDS
COA
| LOT NO. |
DOWNLOAD |
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| 2018-0101 |
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询盘
