CPI-444
产品编号: DC10527
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应用领域
CPI-444 是一种有效的选择性 A2A 受体 (A2AR) 抑制剂,诱导抗肿瘤反应。
| Cas No.: |
1202402-40-1 |
| 名称: |
(S)-7-(5-methylfuran-2-yl)-3-((6-(((tetrahydrofuran-3-yl)oxy)methyl)pyridin-2-yl)methyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-5-amine |
| 别名: |
CPI-444,CPI 444,CPI444 |
| SMILES: |
NC1=NC2=C(N=NN2CC3=NC(CO[C@H]4CCOC4)=CC=C3)C(C5=CC=C(O5)C)=N1 |
| 分子式: |
C20H21N7O3 |
| 分子量: |
407.43 |
| 纯度: |
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| 保存条件: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: |
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| References: |
CPI-444 is an orally administered antagonist of the adenosine A2A receptor. It is designed to block the action of adenosine that is produced by tumors. CPI-444 blocks adenosine from binding to the A2A receptor. Adenosine suppresses the anti-tumor activity of T cells and other immune cells. |
| Kinase Assay: |
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| Animal Administration: |
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| References: |
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MSDS
COA
| LOT NO. |
DOWNLOAD |
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| 2018-0101 |
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