CX6258
产品编号: DC7153
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应用领域
CX-6258是一种强效的、激酶选择性的 pan-Pim 激酶抑制剂，对 Pim-1, Pim-2 和 Pim-3 作用的 IC50 值分别为 5 nM、25 nM 和 16 nM。
| Cas No.: |
1202916-90-2 |
| 名称: |
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| 别名: |
CX-6258; CX 6258 |
| SMILES: |
N1C2=C(C=C(Cl)C=C2)/C(=C\C2=CC=C(C3=CC=CC(C(N4CCCN(C)CC4)=O)=C3)O2)/C1=O |
| 分子式: |
C26H24ClN3O3 |
| 分子量: |
461.94 |
| 纯度: |
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| 保存条件: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: |
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| In Vitro: |
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| References: |
IC50 Value: 5 nM (Pim 1); 25 nM (Pim 2); 16 nM (Pim 3)CX-6258 is a potent, orally efficacious pan-Pim kinases Inhibitor with excellent biochemical potency and kinase selectivity. in vitro: CX-6258 inhibited Flt-3 and Pim-3 (IC50=0.134 and 0.016 uM). At 0. |
| Kinase Assay: |
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| Cell Assay: |
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| Animal Administration: |
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| References: |
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MSDS
| TITLE |
DOWNLOAD |
| MSDS_1588_DC7153_1202916-90-2 |
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COA
| LOT NO. |
DOWNLOAD |
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