DASA-58
产品编号: DC8647
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应用领域
DASA-58是有效的丙酮酸激酶M2 (PKM2) 活化剂，其中AC90 和AC50分别为680 nM，38 nM。
| Cas No.: |
1203494-49-8 |
| 名称: |
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| 别名: |
DASA58; DASA 58 |
| SMILES: |
C1(=CC(N)=CC=C1)S(N1CCCN(S(=O)(=O)C2=CC3OCCOC=3C=C2)CC1)(=O)=O |
| 分子式: |
C19H23N3O6S2 |
| 分子量: |
453.53 |
| 纯度: |
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| 保存条件: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: |
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| In Vivo: |
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| In Vitro: |
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| References: |
DASA-58 is a highly specific small molecule PKM2 activator. DASA-58 inhibits LPS-induced Hif-1a and IL-1b, as well as the expression of a range of other Hif-1a-dependent genes.DASA-58 enhances PKM2 activity by inducing the tetramer formation. |
| Kinase Assay: |
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| Cell Assay: |
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| Animal Administration: |
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| References: |
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MSDS
COA
| LOT NO. |
DOWNLOAD |
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| 2018-0101 |
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询盘
