Apatinib Mesylate
产品编号: DC4101
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应用领域
Apatinib (YN968D1) 是一种口服生物可利用的酪氨酸激酶抑制剂，选择性靶向VEGFR-2，IC50 为 1 nM。Apatinib (YN968D1) 有效抑制 Ret，c-Kit 和 c-Src 活性，IC50 分别为 13，429 和 530 nM。Apatinib (YN968D1) 也抑制 VEGFR-2、c-kit 和 PDGFRβ 的细胞磷酸化。
| Cas No.: |
1218779-75-9 |
| 名称: |
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| SMILES: |
CS(=O)(=O)O.C1CCC(C1)(C#N)C2=CC=C(C=C2)NC(=O)C3=C(N=CC=C3)NCC4=CC=NC=C4 |
| 分子式: |
C25H27N5O4S |
| 分子量: |
493.58 |
| 纯度: |
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| 保存条件: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: |
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| References: |
Description of Apatinib mesylate: Apatinib mesylate is an orally bioavailable, small-molecule receptor tyrosine kinase inhibitor with potential antiangiogenic and antineoplastic activities. Apatinib selectively binds to and inhibits vascular endothelial g |
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MSDS
COA
| LOT NO. |
DOWNLOAD |
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| 2018-0101 |
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