| References: |
GSK2256098 is small molecule FAK kinase inhibitor.FAK inhibitor GSK2256098 inhibits FAK, which may prevent the integrin-mediated activation of several downstream signal transduction pathways, including ERK, JNK/MAPK and PI3K/Akt, thereby inhibiting tumor cell migration, proliferation and survival, and tumor angiogenesis. The tyrosine kinase FAK is normally activated by binding to integrins in the extracellular matrix (ECM) but may be upregulated and constitutively activated in various tumor cell types. For the detailed information of GSK2256098, the solubility of GSK2256098 in water, the solubility of GSK2256098 in DMSO, the solubility of GSK2256098 in PBS buffer, the animal experiment (test) of GSK2256098, the cell expriment (test) of GSK2256098, the in vivo, in vitro and clinical trial test of GSK2256098, the EC50, IC50,and affinity,of GSK2256098, For the detailed information of GSK2256098, the solubility of GSK2256098 in water, the solubility of GSK2256098 in DMSO, the solubility of GSK2256098 in PBS buffer, the animal experiment (test) of GSK2256098, the cell expriment (test) of GSK2256098, the in vivo, in vitro and clinical trial test of GSK2256098, the EC50, IC50,and affinity,of GSK2256098, Please contact DC Chemicals. |
