RN486
产品编号: DC5146
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应用领域
RN486是高活性Btk抑制剂，IC50为4.0 nM。
| Cas No.: |
1242156-23-5 |
| 名称: |
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| 别名: |
RN486; RN-486; RN 486 |
| SMILES: |
C(=O)1C2=C(C=C(C3CC3)C=C2F)C=CN1C1=CC=CC(C2C=C(NC3=NC=C(N4CCN(C)CC4)C=C3)C(=O)N(C)C=2)=C1CO |
| 分子式: |
C35H35FN6O3 |
| 分子量: |
606.69 |
| 纯度: |
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| 保存条件: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: |
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| In Vivo: |
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| In Vitro: |
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| References: |
RN486 is a Bruton's tyrosine kinase (Btk) inhibitor. RN486 not only potently and selectively inhibited the Btk enzyme, but also displayed functional activities in human cell-based assays in multiple cell types, blocking Fcε receptor cross-linking-induced |
| Kinase Assay: |
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| Cell Assay: |
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| Animal Administration: |
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| References: |
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MSDS
COA
| LOT NO. |
DOWNLOAD |
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| 2018-0101 |
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询盘
