GIBH-130
产品编号: DC10490
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应用领域
GIBH-130 是有效的神经炎症抑制剂。GIBH-130 作用于活化的小胶质细胞，显著抑制 IL-1β 分泌，IC50 为 3.4 nM。
| Cas No.: |
1252608-59-5 |
| 名称: |
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| 别名: |
GIBH-130,GIBH 130,GIBH130 |
| SMILES: |
C1=CC=CC=C1C1=CC(C)=C(C(=O)N2CCN(C3=NC=CC=N3)CC2)N=N1 |
| 分子式: |
C20H20N6O |
| 分子量: |
360.41 |
| 纯度: |
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| 保存条件: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: |
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| In Vitro: |
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| References: |
GIBH-130 is a novel inhibitor of neuroinflammation effective in Alzheimer’s disease models. GIBH-130 constitutes a unique chemical probe for pathogenesis research and drug development of AD, and it also suggests microglia-based phenotypic screenings that target neuroinflammation as an effective and feasible strategy to identify novel anti-AD agents. |
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| Animal Administration: |
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| References: |
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MSDS
COA
| LOT NO. |
DOWNLOAD |
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| 2018-0101 |
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询盘
