| References: |
In HEK293 cells, MI-3 accesses the protein target and effectively inhibits the menin-MLL-AF9 interaction. MI-3 effectively blocks MLL fusion protein-mediated leukemic transformation by downregulating the expression of target genes required for MLL fusion protein oncogenic activity. In human MLL leukemia cell lines harboring different MLL translocations, MI-3 effectively blocks cell proliferation, and induces apoptosis. For the detailed information of MI-3 (Menin-MLL Inhibitor), the solubility of MI-3 (Menin-MLL Inhibitor) in water, the solubility of MI-3 (Menin-MLL Inhibitor) in DMSO, the solubility of MI-3 (Menin-MLL Inhibitor) in PBS buffer, the animal experiment (test) of MI-3 (Menin-MLL Inhibitor), the cell expriment (test) of MI-3 (Menin-MLL Inhibitor), the in vivo, in vitro and clinical trial test of MI-3 (Menin-MLL Inhibitor), the EC50, IC50,and affinity,of MI-3 (Menin-MLL Inhibitor), For the detailed information of MI-3 (Menin-MLL Inhibitor), the solubility of MI-3 (Menin-MLL Inhibitor) in water, the solubility of MI-3 (Menin-MLL Inhibitor) in DMSO, the solubility of MI-3 (Menin-MLL Inhibitor) in PBS buffer, the animal experiment (test) of MI-3 (Menin-MLL Inhibitor), the cell expriment (test) of MI-3 (Menin-MLL Inhibitor), the in vivo, in vitro and clinical trial test of MI-3 (Menin-MLL Inhibitor), the EC50, IC50,and affinity,of MI-3 (Menin-MLL Inhibitor), Please contact DC Chemicals. |
