ML-224
产品编号: DC7781
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应用领域
ML224(NCGC00242364; ANTAG3)是促甲状腺激素受体TSHR反激动剂，IC50值为2.3uM。
| Cas No.: |
1338824-21-7 |
| 名称: |
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| 别名: |
NCGC00242364，ANTAG3，ML-224，ML 224 |
| SMILES: |
C1=C(NC(=O)C)C=C(C)C(OCC2=C(OC)C=CC(C3NC4C=CC=CC=4C(=O)N3CC3=CC=CO3)=C2)=C1C |
| 分子式: |
C31H31N3O5 |
| 分子量: |
525.59 |
| 纯度: |
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| 保存条件: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: |
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| In Vivo: |
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| In Vitro: |
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| References: |
ANTAG3 is selective for TSHR inhibition; half-maximal inhibitory doses were 2.1 μM for TSHR and greater than 30 μM for LH and FSH receptors. In mice treated with TRH, ANTAG3 lowered serum free T4 by 44% and lowered mRNAs for sodium-iodide cotransporter an |
| Kinase Assay: |
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| Cell Assay: |
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| Animal Administration: |
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| References: |
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MSDS
COA
| LOT NO. |
DOWNLOAD |
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| 2018-0101 |
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询盘
