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应用领域
GNE0877 is a highly potent, selective, and brain-penetrant aminopyrazole leucine-rich repeat kinase 2 (LRRK2) small molecule inhibitor with an IC50 of 3 nM.
| Cas No.: |
1374828-69-9 |
| 名称: |
2-methyl-2-(3-methyl-4-((4-(methylamino)-5-(trifluoromethyl)pyrimidin-2-yl)amino)-1H-pyrazol-1-yl)propanenitrile. |
| 别名: |
GNE-0877; GNE 0877; GNE0877. |
| SMILES: |
CC1=NN(C(C)(C)C#N)C=C1NC2=NC=C(C(F)(F)F)C(NC)=N2 |
| 分子式: |
C14H16F3N7 |
| 分子量: |
339.31895 |
| 纯度: |
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| 保存条件: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: |
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| In Vitro: |
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| References: |
GNE-0877 is a highly potent and selective LRRK2 inhibitor. Leucine-rich repeat kinase 2 (LRRK2) has drawn significant interest in the neuroscience research community because it is one of the most compelling targets For a potential disease-modifying Parki |
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| Animal Administration: |
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MSDS
COA
| LOT NO. |
DOWNLOAD |
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| 2018-0101 |
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