| References: |
High affinity, selective σ1 agonist (Ki values are 2.2 and 13091 nM for σ1 and σ2 receptors respectively). Selective over PCP receptors (IC50 > 100000 nM) and several other receptor systems. Produces antiamnesic and antitussive effects in vivo. Also exhibits protective effects in PC6.3 cells expressing mutant huntingtin by activating NF-κB signaling. For the detailed information of PRE-084 hydrochloride, the solubility of PRE-084 hydrochloride in water, the solubility of PRE-084 hydrochloride in DMSO, the solubility of PRE-084 hydrochloride in PBS buffer, the animal experiment (test) of PRE-084 hydrochloride, the cell expriment (test) of PRE-084 hydrochloride, the in vivo, in vitro and clinical trial test of PRE-084 hydrochloride, the EC50, IC50,and affinity,of PRE-084 hydrochloride, For the detailed information of PRE-084 hydrochloride, the solubility of PRE-084 hydrochloride in water, the solubility of PRE-084 hydrochloride in DMSO, the solubility of PRE-084 hydrochloride in PBS buffer, the animal experiment (test) of PRE-084 hydrochloride, the cell expriment (test) of PRE-084 hydrochloride, the in vivo, in vitro and clinical trial test of PRE-084 hydrochloride, the EC50, IC50,and affinity,of PRE-084 hydrochloride, Please contact DC Chemicals. |
