RI-2

产品编号: DC8226 Featured
RI-2
结构式
1417162-36-7
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中国地区超过5000个高品质化合物库存
应用领域
RI-2 是一种可逆的 RAD51 抑制剂,IC50 值为 44.17 μM,能够特异性地抑制人体细胞中的同源重组修复。
Cas No.: 1417162-36-7
名称:
别名: RI2,RI 2
SMILES: COC1=CC=C(C=C1)C2=C(C(=O)N(C2=O)C3=CC(=C(C=C3)Cl)Cl)N4CCOCC4
分子式: C21H18Cl2N2O4
分子量: 433.28
纯度:
保存条件: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description:
In Vivo:
In Vitro:
References: RI-2 is an optimized RAD51 inhibitor with an IC50 of 44.17 μM in the standard DNA binding assay; specifically inhibits HR(Homologous recombination) repair in human cells. RI-2 appears to bind reversibly to the same site on the RAD51 protein as does RI-1. Like RI-1, RI-2 specifically inhibits HR repair in human cells. For the detailed information of RI-2, the solubility of RI-2 in water, the solubility of RI-2 in DMSO, the solubility of RI-2 in PBS buffer, the animal experiment (test) of RI-2, the cell expriment (test) of RI-2, the in vivo, in vitro and clinical trial test of RI-2, the EC50, IC50,and affinity,of RI-2, For the detailed information of RI-2, the solubility of RI-2 in water, the solubility of RI-2 in DMSO, the solubility of RI-2 in PBS buffer, the animal experiment (test) of RI-2, the cell expriment (test) of RI-2, the in vivo, in vitro and clinical trial test of RI-2, the EC50, IC50,and affinity,of RI-2, Please contact DC Chemicals.
Kinase Assay:
Cell Assay:
Animal Administration:
References:
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
产品编号 产品名称 应用领域
DC8226 RI-2 RI-2 是一种可逆的 RAD51 抑制剂,IC50 值为 44.17 μM,能够特异性地抑制人体细胞中的同源重组修复。
DC7264 RI-1 RI-1是RAD51抑制剂,IC50在5到30 μM之间。