GTS 21 2HCl(DMXBA)

产品编号: DC8303 Featured
GTS 21 2HCl(DMXBA)
结构式
156223-05-1
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中国地区超过5000个高品质化合物库存
应用领域
GTS-21二盐酸盐是一种选择性α7烟碱型乙酰胆碱受体 (α7nAChR) 激动剂。
Cas No.: 156223-05-1
名称: 3-[(2,4-Dimethoxyphenyl)methylene]-3,4,5,6-tetrahydro-2,3'-bipyridine dihydrochloride
别名: GTS21,GTS 21,GTS-21
SMILES: COC1=CC(=C(C=C1)/C=C/2\CCCN=C2C3=CN=CC=C3)OC.Cl.Cl
分子式: C19H20N2O2.2HCl
分子量: 381.3
纯度:
保存条件: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description:
In Vivo:
In Vitro:
References: Partial agonist of α7 nicotinic acetylcholine receptors (nAChRs); also a weak α4β2 and 5-HT3 antagonist at micromolar concentrations. Exhibits improved sensory inhibition in DBA/2 mice following both acute and chronic administration. Also shown to improve memory in several animal models; facilitates hippocampal long-term potentiation. For the detailed information of GTS 21 2HCl(DMXBA), the solubility of GTS 21 2HCl(DMXBA) in water, the solubility of GTS 21 2HCl(DMXBA) in DMSO, the solubility of GTS 21 2HCl(DMXBA) in PBS buffer, the animal experiment (test) of GTS 21 2HCl(DMXBA), the cell expriment (test) of GTS 21 2HCl(DMXBA), the in vivo, in vitro and clinical trial test of GTS 21 2HCl(DMXBA), the EC50, IC50,and affinity,of GTS 21 2HCl(DMXBA), For the detailed information of GTS 21 2HCl(DMXBA), the solubility of GTS 21 2HCl(DMXBA) in water, the solubility of GTS 21 2HCl(DMXBA) in DMSO, the solubility of GTS 21 2HCl(DMXBA) in PBS buffer, the animal experiment (test) of GTS 21 2HCl(DMXBA), the cell expriment (test) of GTS 21 2HCl(DMXBA), the in vivo, in vitro and clinical trial test of GTS 21 2HCl(DMXBA), the EC50, IC50,and affinity,of GTS 21 2HCl(DMXBA), Please contact DC Chemicals.
Kinase Assay:
Cell Assay:
Animal Administration:
References:
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
产品编号 产品名称 应用领域
DC8902 PNU282987 PNU282987 in stock,price: 350 USD/100mg. PNU-282987 is a selective α7 nicotinic acetylcholine receptor(α7 nAChR) agonist with Ki of 26 nM; no affinity for α1β1γδ and α3β4 nAChRs (IC50 ≥ 60?
DC8303 GTS 21 2HCl(DMXBA) GTS-21二盐酸盐是一种选择性α7烟碱型乙酰胆碱受体 (α7nAChR) 激动剂。
DC12033 (S)-B-973B (-)-(S)-B-973B 为一种有效的 α7 nAChR 正向别构调节剂,具有镇痛作用。