Cisplatin

产品编号: DC2099 Featured
Cisplatin
结构式
15663-27-1
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中国地区超过5000个高品质化合物库存
应用领域
Cisplatin (CDDP) 是一种抗肿瘤的化疗剂,它与 DNA 交联引起癌细胞中 DNA 损伤。Cisplatin 可激活铁死亡 (ferroptosis) 并诱导自噬 (autophagy)。
Cas No.: 15663-27-1
名称: Cisplatin is an inorganic and water-soluble platinum complex, which is able to inhibit DNA synthesis by conforming DNA adducts.
别名: cisplatinum, CDDP, Platinol and Platinol-AQ
SMILES: [Pt](Cl)Cl.N.N
分子式: Cl2H6N2Pt
分子量: 300.05
纯度:
保存条件: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description:
In Vivo:
In Vitro:
References: Cisplatin is an inorganic platinum agent (cis-diamminedichloroplatinum) with antineoplastic activity. Cisplatin Forms highly reactive, charged, platinum complexes which bind to nucleophilic groups such as GC-rich sites in DNA, inducing intrastrand and interstrand DNA cross-links, as well as DNA-protein cross-links. These cross-links result in apoptosis and cell growth inhibition. Check For active clinical trials or closed clinical trials using this agent. (NCI Thesaurus) For the detailed information about the solubility of Cisplatin in water, the solubility of Cisplatin in DMSO, the solubility of Cisplatin in PBS buffer, the animal experiment(test) of Cisplatin,the in vivo,in vitro and clinical trial test of Cisplatin,the cell experiment(test) of Cisplatin,the IC50, EC50 and Affinity of Cisplatin, please contact DC Chemicals.
Kinase Assay:
Cell Assay:
Animal Administration:
References:
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
产品编号 产品名称 应用领域
DC2099 Cisplatin Cisplatin (CDDP) 是一种抗肿瘤的化疗剂,它与 DNA 交联引起癌细胞中 DNA 损伤。Cisplatin 可激活铁死亡 (ferroptosis) 并诱导自噬 (autophagy)。