AZ191
产品编号: DC7746
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应用领域
AZ191 是 DYRK1B 高效选择性抑制剂，IC50 值 17 nM。
| Cas No.: |
1594092-37-1 |
| 名称: |
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| 别名: |
AZ-191,AZ 191 |
| SMILES: |
CN1CCN(CC1)C2=CC(=C(C=C2)NC3=NC=CC(=N3)C4=CN(C5=C4C=CN=C5)C)OC |
| 分子式: |
C24H27N7O |
| 分子量: |
429.52 |
| 纯度: |
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| 保存条件: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: |
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| In Vitro: |
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| References: |
AZ191 selectively inhibits DYRK1B serine/threonine kinase activity with no effect on tyrosine kinase autophosphorylation. In HEK-293 cells, AZ191 also displays much greater potency for DYRK1B over DYRK1A, inhibiting CCND1 phosphorylation. In HD1B cells, A |
| Kinase Assay: |
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| Cell Assay: |
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| Animal Administration: |
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| References: |
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MSDS
| TITLE |
DOWNLOAD |
| MSDS_1945_DC7746_1594092-37-1 |
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COA
| LOT NO. |
DOWNLOAD |
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询盘
