MC-Val-Cit-PAB
产品编号: DC10120
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应用领域
MC-Val-Cit-PAB是可被组织蛋白酶切割的ADC连接桥，用于制备抗体-药物偶联物。 美国FDA批准的药物，如brentuximab vedotin使用了该连接桥。
| Cas No.: |
159857-80-4 |
| 名称: |
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| 别名: |
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| SMILES: |
CC(C)[C@@H](C(=O)N[C@@H](CCCNC(=O)N)C(=O)NC1=CC=C(C=C1)CO)NC(=O)CCCCCN2C(=O)C=CC2=O |
| 分子式: |
C28H40N6O7 |
| 分子量: |
572.66 |
| 纯度: |
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| 保存条件: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: |
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| References: |
MC-Val-Cit-PAB, also known as MC-Val-Cit-PAB-OH, is a cathepsin cleavable ADC peptide linker. MC-Val-Cit-PAB is useful for making ADC conjugate (antibody-drug conjugate). FDA approved drugs such as brentuximab vedotin used this linker. |
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MSDS
| TITLE |
DOWNLOAD |
| MSDS_103_DC10120_159857-80-4 |
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COA
| LOT NO. |
DOWNLOAD |
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