Mc-Val-Cit-PABC-PNP(VCMMAE linker)

产品编号: DC8461 Featured
Mc-Val-Cit-PABC-PNP(VCMMAE linker)
结构式
159857-81-5
此产品仅供科研所需,我们不出售给病人
​我们将匹配市场上最好的价格给您
Email:order@dcbio.cn
免费咨询电话:4008862077
我们的合作伙伴:
  • 20
  • 19
  • 18
  • 17
  • 16
  • 15
  • 14
  • 12
  • 11
  • 10
  • 9
  • 8
  • 13
  • 6
  • 5
  • 4
  • 3
  • 2
  • 1
中国地区超过5000个高品质化合物库存
应用领域
Mc-Val-Cit-PABC-PNP是用于合成抗体-药物偶联物 (ADCs) 的,可降解的组织蛋白酶连接桥 (ADC linker)。
Cas No.: 159857-81-5
名称:
别名: Maleimidocaproyl-L-valine-L-citrulline-p-aminobenzyl alcohol p-nitrophenyl carbonate
SMILES: N(C1=CC=C(COC(OC2=CC=C([N+]([O-])=O)C=C2)=O)C=C1)C(=O)[C@H](NC(=O)[C@@H](C(C)C)NC(=O)CCCCCN1C(=O)C=CC1=O)CCCNC(N)=O
分子式: C35H43N7O11
分子量: 737.76
纯度:
保存条件: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description:
In Vivo:
In Vitro:
References: Mc-Val-Cit-PABC-PNP is a cathepsin cleavable ADC peptide linker. For example, FDA approved drug, brentuximab vedotin, adopts this linker. For the detailed information of Mc-Val-Cit-PABC-PNP, the solubility of Mc-Val-Cit-PABC-PNP in water, the solubility of Mc-Val-Cit-PABC-PNP in DMSO, the solubility of Mc-Val-Cit-PABC-PNP in PBS buffer, the animal experiment (test) of Mc-Val-Cit-PABC-PNP, the cell expriment (test) of Mc-Val-Cit-PABC-PNP, the in vivo, in vitro and clinical trial test of Mc-Val-Cit-PABC-PNP, the EC50, IC50,and affinity,of Mc-Val-Cit-PABC-PNP, For the detailed information of Mc-Val-Cit-PABC-PNP, the solubility of Mc-Val-Cit-PABC-PNP in water, the solubility of Mc-Val-Cit-PABC-PNP in DMSO, the solubility of Mc-Val-Cit-PABC-PNP in PBS buffer, the animal experiment (test) of Mc-Val-Cit-PABC-PNP, the cell expriment (test) of Mc-Val-Cit-PABC-PNP, the in vivo, in vitro and clinical trial test of Mc-Val-Cit-PABC-PNP, the EC50, IC50,and affinity,of Mc-Val-Cit-PABC-PNP, Please contact DC Chemicals.
Kinase Assay:
Cell Assay:
Animal Administration:
References:
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
产品编号 产品名称 应用领域
DC8461 Mc-Val-Cit-PABC-PNP(VCMMAE linker) Mc-Val-Cit-PABC-PNP是用于合成抗体-药物偶联物 (ADCs) 的,可降解的组织蛋白酶连接桥 (ADC linker)。