TH 287
产品编号: DC7725
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应用领域
TH287是MTH1 (NUDT1)高效选择性抑制剂，IC50值0.8nM，对MTH2, NUDT5, NUDT12, NUDT14等抑制力弱。
| Cas No.: |
1609960-30-6 |
| 名称: |
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| 别名: |
TH287,TH-287 |
| SMILES: |
CNC1=NC(=NC(=C1)C2=C(C(=CC=C2)Cl)Cl)N |
| 分子式: |
C11H10Cl2N4 |
| 分子量: |
269.13 |
| 纯度: |
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| 保存条件: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: |
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| In Vitro: |
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| References: |
First-in-class MTH1 inhibitor (IC50 value 0.8 nM) that selectively and effectively kills U2OS and other cancer cell lines, with considerably less toxicity towards several primary or immortalized cells. TH 287 shows no relevant inhibitory effect for any of |
| Kinase Assay: |
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| Cell Assay: |
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| Animal Administration: |
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| References: |
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MSDS
| TITLE |
DOWNLOAD |
| MSDS_1928_DC7725_1609960-30-6 |
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COA
| LOT NO. |
DOWNLOAD |
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