cyclo(-RGDfK)

产品编号: DC8055 Featured
cyclo(-RGDfK)
结构式
161552-03-0
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中国地区超过5000个高品质化合物库存
应用领域
Cyclo(-RGDfK) 是有效,选择性的整合素 αvβ3 抑制剂,其 IC50 值为 0.94 nM。
Cas No.: 161552-03-0
名称: 2-[(2S,5R,8S,11S)-8-(4-aminobutyl)-5-benzyl-11-[3-(diaminomethylideneamino)propyl]-3,6,9,12,15-pentaoxo-1,4,7,10,13-pentazacyclopentadec-2-yl]acetic acid
别名:
SMILES: C(O)(=O)C[C@@H]1C(=O)N[C@@H](CC2=CC=CC=C2)C(=O)N[C@H](CCCCN)C(=O)N[C@H](CCCN(N)(N)=C)C(=O)NCC(=O)N1
分子式: C27H41N9O7
分子量: 603.7
纯度:
保存条件: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description:
In Vivo:
In Vitro:
References: cyclo(-RGDfK,-Arg-Gly-Asp-D-Phe-Lys)) is a selective αvβ3-integrin antagonist. In one study where this peptide was labeled with 125I, it was found to bind specifically and with high affinity to αvβ3 receptors on neovascular blood vessel sections of different major human cancers. The integrin alpha(IIb)beta(3)-specific cyclic hexapeptide contains an Arg-Gly-Asp (RGD) sequence. For the detailed information of cyclo(-RGDfK), the solubility of cyclo(-RGDfK) in water, the solubility of cyclo(-RGDfK) in DMSO, the solubility of cyclo(-RGDfK) in PBS buffer, the animal experiment (test) of cyclo(-RGDfK), the cell expriment (test) of cyclo(-RGDfK), the in vivo, in vitro and clinical trial test of cyclo(-RGDfK), the EC50, IC50,and affinity,of cyclo(-RGDfK), For the detailed information of cyclo(-RGDfK), the solubility of cyclo(-RGDfK) in water, the solubility of cyclo(-RGDfK) in DMSO, the solubility of cyclo(-RGDfK) in PBS buffer, the animal experiment (test) of cyclo(-RGDfK), the cell expriment (test) of cyclo(-RGDfK), the in vivo, in vitro and clinical trial test of cyclo(-RGDfK), the EC50, IC50,and affinity,of cyclo(-RGDfK), Please contact DC Chemicals.
Kinase Assay:
Cell Assay:
Animal Administration:
References:
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
产品编号 产品名称 应用领域
DC8399 Cyclo(RGDyK) Cyclo(RGDyK) trifluoroacetate 是一种有效的选择性 αVβ3 整联蛋白 (integrin) 抑制剂,IC50 为 20 nM。
DC8055 cyclo(-RGDfK) Cyclo(-RGDfK) 是有效,选择性的整合素 αvβ3 抑制剂,其 IC50 值为 0.94 nM。