Terutroban
产品编号: DC9609
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应用领域
Terutroban是一种血栓素-前列腺素受体拮抗剂。
| Cas No.: |
165538-40-9 |
| 名称: |
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| 别名: |
S-18886 |
| SMILES: |
O=C(O)CCC1=C2CC[C@@H](NS(=O)(C3=CC=C(Cl)C=C3)=O)CC2=CC=C1C |
| 分子式: |
C20H22ClNO4S |
| 分子量: |
407.911 |
| 纯度: |
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| 保存条件: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: |
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| In Vitro: |
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| References: |
Terutroban is a thromboxane/prostaglandin endoperoxide receptor antagonist.
in vivo: Terutroban is a selective antagonist of the thromboxane/prostaglandin endoperoxide receptor, in preventing retinal ischaemia in a model of diabetes in rats. Terutroban significantly protect retinal vascularity from ischaemia in experimental diabetes, and this result could be attributed not only to its antiplatelet/antithrombotic activities but also to its vascular properties.Terutroban has antiplatelet properties. In addition, Terutroban has shown to improve flow-mediated dilatation of the brachial artery after a single administration in patients with coronary artery disease.Terutroban is a potent antithrombotic agent and also possesses antiatherosclerotic and antivasoconstrictor properties. |
| Kinase Assay: |
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| Cell Assay: |
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| Animal Administration: |
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| References: |
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MSDS
COA
| LOT NO. |
DOWNLOAD |
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| 2018-0101 |
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