Ro 48-8071 fumarate
产品编号: DC7933
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应用领域
Ro 48-8071 fumarate 是氧化鲨烯环化酶 (Oxidosqualene cyclase) 抑制剂，IC50 约为 6.5 nM。
| Cas No.: |
189197-69-1 |
| 名称: |
[4′-[6-(Allylmethylamino)hexyloxy]-4-bromo-2′-fluorobenzophenone fumarate |
| 别名: |
Ro 488071,Ro48-8071,Ro-48-8071 |
| SMILES: |
CN(CCCCCCOC1=CC(=C(C=C1)C(=O)C2=CC=C(C=C2)Br)F)CC=C.C(=C/C(=O)O)\C(=O)O |
| 分子式: |
C27H31BrFNO6 |
| 分子量: |
564.44 |
| 纯度: |
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| 保存条件: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: |
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| References: |
Ro 48-8.071 blocked human liver OSC and cholesterol synthesis in HepG2 cells in the nanomolar range; in cells it triggered the production of monooxidosqualene, dioxidosqualene, and epoxycholesterol . Ro 48-8071 showed potent noncompetitive inhibition of b |
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MSDS
| TITLE |
DOWNLOAD |
| MSDS_2024_DC7933_189197-69-1 |
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COA
| LOT NO. |
DOWNLOAD |
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