Ro 61-8048
产品编号: DC7656
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应用领域
Ro 61-8048是一种有效的和选择性犬尿氨酸羟化酶（kynurenine hydroxylase）抑制剂，IC50为37 nM。
| Cas No.: |
199666-03-0 |
| 名称: |
3,4-Dimethoxy-N-[4-(3-nitrophenyl)-2-thiazolyl]benzenesulfonamide |
| 别名: |
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| SMILES: |
C(S(NC1=NC(C2=CC=CC([N+]([O-])=O)=C2)=CS1)(=O)=O)1=CC=C(OC)C(OC)=C1 |
| 分子式: |
C17H15N3O6S2 |
| 分子量: |
421.45 |
| 纯度: |
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| 保存条件: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: |
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| In Vivo: |
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| In Vitro: |
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| References: |
Potent and competitive kynurenine 3-hydroxylase inhibitor (Ki = 4.8 nM, IC50 = 37 nM). Increases kynurenic acid levels to concentrations that antagonize the glycine site of NMDA receptors. Brain penetrant and exhibits antidystonic, anticonvulsant and neur |
| Kinase Assay: |
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| Cell Assay: |
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| Animal Administration: |
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| References: |
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MSDS
COA
| LOT NO. |
DOWNLOAD |
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| 2018-0101 |
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询盘
