Semaxanib (SU5416)
产品编号: DC7290
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应用领域
Semaxinib (SU5416) 是有效，选择性的 VEGFR (Flk-1/KDR) 抑制剂，IC50 为1.23 μM。
| Cas No.: |
204005-46-9 |
| 名称: |
2H-Indol-2-one,3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylene]-1,3-dihydro-,(3Z)- |
| 别名: |
Semaxinib; SU-5416; SU 5416 |
| SMILES: |
CC1=CC(=C(N1)/C=C\2/C3=CC=CC=C3NC2=O)C |
| 分子式: |
C15H14N2O |
| 分子量: |
238.28 |
| 纯度: |
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| 保存条件: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: |
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| In Vitro: |
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| References: |
Semaxanib inhibits VEGF-dependent phosphorylation of the Flk-1 receptor in Flk-1-overexpressing NIH 3T3 cells with IC50 of 1.04 μM. Semaxanib inhibits PDGF-dependent autophosphorylation in NIH 3T3 cells with IC50 of 20.3 μM. Semaxanib inhibits VEGF- and F |
| Kinase Assay: |
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| Cell Assay: |
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| Animal Administration: |
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| References: |
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MSDS
COA
| LOT NO. |
DOWNLOAD |
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| 2018-0101 |
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