| Cas No.: | 2098836-45-2 |
| 名称: | (2S,4R)-1-((R)-2-acetamido-3-((6-(2-((S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)acetamido)hexyl)thio)-3-methylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide |
| 别名: | BRD4 PROTAC AT1 |
| SMILES: | N(C(=O)[C@H](NC(=O)C)C(SCCCCCCNC(=O)C[C@H]1N=C(C2=CC=C(Cl)C=C2)C2C(C)=C(C)SC=2N2C(C)=NN=C21)(C)C)1C[C@@H](O)C[C@@H]1C(NCC1=CC=C(C2SC=NC=2C)C=C1)=O |
| 分子式: | C48H58ClN9O5S3 |
| 分子量: | 972.68 |
| 纯度: | |
| 保存条件: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: | |
| In Vivo: | |
| In Vitro: | |
| References: | BRD4 degrader AT1 is a highly selective BED4 degrader (PROTAC), exhibits highly selective depletion of BRD4 in cells with negligible activity against BRD2 and BRD3. |
| Kinase Assay: | |
| Cell Assay: | |
| Animal Administration: | |
| References: |
MSDS
| TITLE | DOWNLOAD |
| MSDS_671_DC10997_2098836-45-2 |
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COA
| LOT NO. | DOWNLOAD |
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