| References: |
In SIRT2-myc-expressing HeLa cells, AGK2 effectively inhibits the activity of SIRT2, and increases acetylated tubulin. AGK2 protects dopaminergic neurons from α-Syn–induced toxicity in primary midbrain cultures. AGK2 induces both necrosis and caspase-3-dependent apoptosis in C6 glioma cells. SIRT2 also decreases merlin-mutant viability of mouse schwann cells (MSCs) without substantially reducing wild-type MSC viability. In drosophila model of parkinson's disease, AGK2 rescues α-Syn–mediated toxicity and modify aggregation. For the detailed information of AGK2, the solubility of AGK2 in water, the solubility of AGK2 in DMSO, the solubility of AGK2 in PBS buffer, the animal experiment (test) of AGK2, the cell expriment (test) of AGK2, the in vivo, in vitro and clinical trial test of AGK2, the EC50, IC50,and affinity,of AGK2, For the detailed information of AGK2, the solubility of AGK2 in water, the solubility of AGK2 in DMSO, the solubility of AGK2 in PBS buffer, the animal experiment (test) of AGK2, the cell expriment (test) of AGK2, the in vivo, in vitro and clinical trial test of AGK2, the EC50, IC50,and affinity,of AGK2, Please contact DC Chemicals. |
