SB-715992 (Ispinesib)
产品编号: DC5107
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应用领域
Ispinesib 是一种特异性的纺锤体驱动蛋白 KSP 抑制剂，Ki app 值为 1.7 nM。
| Cas No.: |
336113-53-2 |
| 名称: |
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| 别名: |
Ispinesib;SB-715992;SB715992 |
| SMILES: |
C(N(CCCN)[C@H](C1N(CC2=CC=CC=C2)C(=O)C2=C(N=1)C=C(Cl)C=C2)C(C)C)(=O)C1=CC=C(C)C=C1 |
| 分子式: |
C30H33ClN4O2 |
| 分子量: |
517.06 |
| 纯度: |
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| 保存条件: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: |
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| In Vitro: |
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| References: |
Ispinesib (SB 715992) is a potent mitotic kinesin KSP (Eg5) inhibitor with a Ki and an IC50 of 0.6 and 4.1 nM, respectively. Ispinesib (SB 715992) has cytotoxic activity at less than 10 nM in a spectrum of tumor cell lines. Ispinesib (SB 715992) is negati |
| Kinase Assay: |
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| Cell Assay: |
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| Animal Administration: |
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| References: |
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MSDS
COA
| LOT NO. |
DOWNLOAD |
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| 2018-0101 |
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