NSC 185058
产品编号: DC11363
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应用领域
NSC 185058 是一种 ATG4B 抑制剂。ATG4B 是一种主要的半胱氨酸蛋白酶 (cysteine protease)。NSC185058 抑制 ATG4B 从而显著减弱自噬 (autophagic) 活性。
| Cas No.: |
39122-38-8 |
| 名称: |
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| 别名: |
NSC 185058 |
| SMILES: |
S=C(C1=NC=CC=C1)NC2=NC=CC=C2 |
| 分子式: |
C11H9N3S |
| 分子量: |
215.3 |
| 纯度: |
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| 保存条件: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: |
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| In Vitro: |
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| References: |
NSC 185058 is an inhibitor of ATG4B, a cysteine protease that activates LC3B during the initiation of autophagy.It inhibits ATG4B cleavage of LC3B-GST (IC50 = 51 μM) and reduces LC3B lipidation induced by starvation in Saos-2 cells. NSC 185058 (100 μM) re |
| Kinase Assay: |
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| Cell Assay: |
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| Animal Administration: |
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| References: |
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MSDS
| TITLE |
DOWNLOAD |
| MSDS_3101_DC11363_39122-38-8 |
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COA
| LOT NO. |
DOWNLOAD |
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询盘
