10058-F4
产品编号: DC7575
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应用领域
10058-F4是 c-Myc 抑制剂，其阻止c-Myc-Max二聚化和c-Myc靶基因表达的反式激活。
| Cas No.: |
403811-55-2 |
| 名称: |
4-Thiazolidinone, 5-[(4-ethylphenyl)methylene]-2-thioxo |
| 别名: |
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| SMILES: |
CCC1=CC=C(C=C1)/C=C/2\C(=O)NC(=S)S2 |
| 分子式: |
C12H11NOs2 |
| 分子量: |
249.35 |
| 纯度: |
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| 保存条件: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: |
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| In Vivo: |
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| In Vitro: |
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| References: |
10058-F4 inhibits growth of leukemic cells and dimerization of Myc and Max. 10058-F4 induces cell-cycle arrest and apoptosis of AML cells. 10058-F4 arrests AML cells at G0/G1 phase, downregulates c-Myc expression and upregulated CDK inhibitors, p21 and p2 |
| Kinase Assay: |
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| Cell Assay: |
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| Animal Administration: |
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| References: |
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MSDS
COA
| LOT NO. |
DOWNLOAD |
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| 2018-0101 |
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询盘
