ML 161
产品编号: DC7197
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应用领域
Parmodulin 2 (ML161) 是一种蛋白酶激活受体 1 (PAR1) 变构抑制剂，IC50 为 0.26 μM。Parmodulin 2 抑制由 PAR1 肽激动剂或凝血酶诱导的血小板聚集并且显示出细胞保护作用。
| Cas No.: |
423735-93-7 |
| 名称: |
Benzamide,2-bromo-N-[3-[(1-oxobutyl)amino]phenyl]- |
| 别名: |
ML161,ML-161 |
| SMILES: |
C(NC1=CC=CC(NC(=O)CCC)=C1)(=O)C1=CC=CC=C1Br |
| 分子式: |
C17H17BrN2O2 |
| 分子量: |
361.23 |
| 纯度: |
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| 保存条件: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: |
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| In Vitro: |
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| References: |
ML-161 is an allosteric inhibitor of PAR1. ML-161 displays dose-dependent inhibition of thrombin-induced platelet activation, as measured by P-selectin expression. ML-161 displays selective inhibition of SFLLRN and thrombin-induced platelet aggregation, b |
| Kinase Assay: |
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| Cell Assay: |
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| Animal Administration: |
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| References: |
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MSDS
COA
| LOT NO. |
DOWNLOAD |
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| 2018-0101 |
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询盘
