CK-636
产品编号: DC7386
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应用领域
CK-636是具有细胞渗透性的Arp2/3 复合体抑制剂，能抑制肌动蛋白的聚合，对人，裂殖酵母和牛的 IC50 值分别为4 μM，24 μM和32 μM。
| Cas No.: |
442632-72-6 |
| 名称: |
N-[2-(2-Methyl-1H-indol-3-yl)ethyl]-2-thiophenecarboxamide |
| 别名: |
CK636; CK 636; CK-0944636; CK0944636; CK 0944636 |
| SMILES: |
CC1=C(C2=CC=CC=C2N1)CCNC(=O)C3=CC=CS3 |
| 分子式: |
C16H16N2Os |
| 分子量: |
284.38 |
| 纯度: |
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| 保存条件: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: |
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| In Vivo: |
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| In Vitro: |
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| References: |
CK-636 inhibits actin polymerization mediated by Arp2/3 complex in live cells, and reduces the Formation of actin filament comet tails by Listeria in infected SKOV3 cells. CK-636 inhibits lamellipodia Formation at the leading edges of migrating T cells |
| Kinase Assay: |
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| Cell Assay: |
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| Animal Administration: |
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| References: |
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MSDS
COA
| LOT NO. |
DOWNLOAD |
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| 2018-0101 |
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询盘
