Vandetanib (ZD6474)
产品编号: DC3134
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应用领域
Vandetanib是有效的 VEGFR2 抑制剂，IC50 为40 nM。
| Cas No.: |
443913-73-3 |
| 名称: |
N-(4-bromo-2-fluorophenyl)-6-methoxy-7-((1-methylpiperidin-4-yl)methoxy)quinazolin-4-amine |
| 别名: |
ZD6474,AZD-6474 |
| SMILES: |
CN1CCC(CC1)COC2=C(C=C3C(=C2)N=CN=C3NC4=C(C=C(C=C4)Br)F)OC |
| 分子式: |
C22H24BrFN4O2 |
| 分子量: |
475.35 |
| 纯度: |
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| 保存条件: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: |
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| In Vitro: |
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| References: |
Vandetanib is an orally bioavailable 4-anilinoquinazoline. Vandetanib selectively inhibits the tyrosine kinase activity of vascular endothelial growth factor receptor 2 (VEGF2), thereby blocking VEGF-stimulated endothelial cell proliferation and migration |
| Kinase Assay: |
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| Animal Administration: |
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MSDS
| TITLE |
DOWNLOAD |
| MSDS_1333_DC3134_443913-73-3 |
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COA
| LOT NO. |
DOWNLOAD |
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