| Cas No.: | 459789-99-2 |
| 名称: | (4R)-4-[(3R,5S,6R,7R,8S,9S,10S,13R,14S,17R)-6-ethyl-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid |
| 别名: | 6-ECDCA, Obeticholic acid, INT-747, INT747, 6alpha-Ethyl-chenodeoxycholic acid, UNII-0462Z4S4OZ, 459789-99-2, 6-ETHYL-CHENODEOXYCHOLIC ACID |
| SMILES: | CC[C@@H]1[C@@H]2C[C@@H](CC[C@@]2([C@H]3CC[C@]4([C@H]([C@@H]3[C@@H]1O)CC[C@@H]4[C@H](C)CCC(=O)O)C)C)O |
| 分子式: | C26H44O4 |
| 分子量: | 420.63 |
| 纯度: | |
| 保存条件: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: | |
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| In Vitro: | |
| References: | INT-747(Obeticholic acid; 6-ECDCA) is a potent and selective FXR agonist(EC50=99 nM) endowed with anticholestatic activity. in vitro: The exposure of rat hepatocytes to 1 microM 6-ECDCA caused a 3- to 5-fold induction of small heterodimer partner (Shp) an |
| Kinase Assay: | |
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| Animal Administration: | |
| References: |
MSDS
| TITLE | DOWNLOAD |
| MSDS_1759_DC7430_459789-99-2 |
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COA
| LOT NO. | DOWNLOAD |
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