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中国地区超过5000个高品质化合物库存
应用领域
PNU-120596 is a positive allosteric modulator of α7 nAChR with EC50 of 216 nM.
| Cas No.: |
501925-31-1 |
| 名称: |
1-(5-chloro-2,4-dimethoxyphenyl)-3-(5-methylisoxazol-3-yl)urea |
| 别名: |
Nsc 216666 |
| SMILES: |
O=C(NC1=CC(Cl)=C(C=C1OC)OC)NC2=NOC(C)=C2 |
| 分子式: |
C13H14ClN3O4 |
| 分子量: |
311.72 |
| 纯度: |
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| 保存条件: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: |
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| In Vivo: |
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| In Vitro: |
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| References: |
PNU-120596 increases agonist (Ach)-evoked calcium flux mediated by an engineered variant of the human α7 nAChR. PNU-120596 increases agonists (choline and ACh)-evoked currents mediated by wild-type receptors and also demonstrates a pronounced prolongation |
| Kinase Assay: |
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| Cell Assay: |
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| Animal Administration: |
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| References: |
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MSDS
COA
| LOT NO. |
DOWNLOAD |
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| 2018-0101 |
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询盘
