GW441756
产品编号: DC7145
Featured
我们的合作伙伴:
中国地区超过5000个高品质化合物库存
应用领域
GW 441756是特异的高活性原肌球蛋白相关激酶A（TrkA）抑制剂，IC50为2 nM，对c-Raf1和CDK2几乎无活性。
| Cas No.: |
504433-23-2 |
| 名称: |
2H-Pyrrolo[3,2-b]pyridin-2-one,1,3-dihydro-3-[(1-methyl-1H-indol-3-yl)methylene]- |
| 别名: |
GW 441756; GW-441756 |
| SMILES: |
CN1C=C(C2=CC=CC=C21)/C=C\3/C4=C(C=CC=N4)NC3=O |
| 分子式: |
C17H13N3O |
| 分子量: |
275.3 |
| 纯度: |
|
| 保存条件: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: |
|
| In Vivo: |
|
| In Vitro: |
|
| References: |
GW441756 can specifically block TrkA-induced cell death in a dose-dependent manner. GW441756 can block TrkA-mediated γH2AX production and apoptosis in TrkA-overexpressing cells. For the detailed information of GW441756, the solubility of GW441756 in water |
| Kinase Assay: |
|
| Cell Assay: |
|
| Animal Administration: |
|
| References: |
|
MSDS
COA
| LOT NO. |
DOWNLOAD |
|
|
| 2018-0101 |
|
询盘
