| References: |
The Ki values of (−)-naloxone for the MOR, KOR, and DOR are 0.559 nM, 4.91 nM, and 36.5 nM, respectively. Naloxone HCl Dihydrate binds to the MOR with approximately 9-fold greater affinity relative to the KOR and around 60-fold greater affinity relative to the DOR.The combination of Naloxone HCl Dihydrate (0.5 mg/kg, i.p.) with tramadol (22 mg/kg) decreases the antiallodynic effect of tramadol. For the detailed information of Naloxone HCl Dihydrate, the solubility of Naloxone HCl Dihydrate in water, the solubility of Naloxone HCl Dihydrate in DMSO, the solubility of Naloxone HCl Dihydrate in PBS buffer, the animal experiment (test) of Naloxone HCl Dihydrate, the cell expriment (test) of Naloxone HCl Dihydrate, the in vivo, in vitro and clinical trial test of Naloxone HCl Dihydrate, the EC50, IC50,and affinity,of Naloxone HCl Dihydrate, For the detailed information of Naloxone HCl Dihydrate, the solubility of Naloxone HCl Dihydrate in water, the solubility of Naloxone HCl Dihydrate in DMSO, the solubility of Naloxone HCl Dihydrate in PBS buffer, the animal experiment (test) of Naloxone HCl Dihydrate, the cell expriment (test) of Naloxone HCl Dihydrate, the in vivo, in vitro and clinical trial test of Naloxone HCl Dihydrate, the EC50, IC50,and affinity,of Naloxone HCl Dihydrate, Please contact DC Chemicals. |
