AMG9810
产品编号: DC10132
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应用领域
AMG9810是选择性和竞争性的香草素受体1 (TRPV1) 拮抗剂，对人类和大鼠TRPV1的IC50值分别为24.5 和 85.6 nM。
| Cas No.: |
545395-94-6 |
| 名称: |
(2E)-N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-3-[4-(1,1-dimethylethyl)phenyl]-2-propenamide |
| 别名: |
AMG 9810,AMG-9810 |
| SMILES: |
CC(C)(C)C1=CC=C(C=C1)/C=C/C(=O)NC2=CC3=C(C=C2)OCCO3 |
| 分子式: |
C24H24ClFN2O |
| 分子量: |
337.41 |
| 纯度: |
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| 保存条件: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: |
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| In Vitro: |
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| References: |
AMG9810 is a potent and selective, competitive vanilloid TRPV1 receptor antagonist (IC50 = 17 nM). AMG9810 inhibits capsaicin-, proton-, heat- and endogenous ligand-induced activation of human and rat recombinant TRPV1 receptors. Displays antihyperalgesic properties in a rat model of inflammatory pain. |
| Kinase Assay: |
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| Cell Assay: |
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| Animal Administration: |
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| References: |
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MSDS
COA
| LOT NO. |
DOWNLOAD |
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| 2018-0101 |
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询盘
